THE USE OF HEPATOPROTECTORS IN THE PHARMACOTHERAPY OF COMORBID VASCULITIS WITH CRYOGLOBULINEMIC SYNDROME
Keywords:
medicine, vasculitis, comorbidity, pharmacotherapy, pharmacoeconomic, ATC-code A16AA02
Abstract
The article presents studies concerning the pharmaceutical therapy and provision among patients with comorbid vasculitis with cryoglobulinemic syndrome. Information from various authors on subject and particularities of its treatment was analyzed. While conducting literature review, used pharmaceutical and economic, organizational and legal, forensic and pharmaceutical approaches and methodology in studying of particularities of pharmaceutical therapy and provision among patients with above-mentioned illness. ABC/VEN analysis was used in study to select the most effective and safe drugs, while keeping in mind treatment costs in Ukraine. The matrix of the consolidated ABC/VEN analysis of drugs for treatment of mentioned patients with comorbid vasculitis in Ukraine using hepatoprotectors was developed during the study. Further researches needed in order to implement into the state programs for pharmaceutical therapy and provision among patients with comorbid vasculitis with cryoglobulinemic syndrome. Importance in making appropriate administrative and managerial decisions while detecting the comorbid vasculitis in order to improve the use of drugs in healthcare facilities was proved.
References
1. ATC-classification, 2020. Compendium on-line. Retrieved from: http://compendium.com.ua/atc
2. (accessed 20.02.2021)
3. Beketova T.V., Blank L.M., Lila A.M. (2019) COVID-19 in a patient with ANCA-associated systemic vasculitis, receiving anti-B cell therapy (rituximab). Rheumatology Science and Practice. Retrieved from: https://rsp.mediar-press.net/rsp/article/view/2889?locale=ru_RU# (accessed 04.02.2021)
4. Fellner С. (2016) Biologics will pump up the Vasculitis Market. Pharmacy and Therapeutics, vol. 41, no. 4, pp. 258–260. Retrieved from: https://pubmed.ncbi.nlm.nih.gov/27069346/ (accessed 21.12.2020)
5. Hayduchok I.G., Shapovalova V.O., Shapovalov V.V. (Jr.), Shapovalov V.V. (Jr.) (2020) Control regime of antibacterial drugs for pharmacotherapy of coronavirus disease (COVID-19) among patients with dual disorders. An information letter about innovations Ukrmedpatentinform of the Ministry of Health of Ukraine. Kyiv: Ukrmedpatentinform of the Ministry of Health of Ukraine, no. 230–2020, 6 p.
6. Hayduchok I.G., Shapovalova V.O., Shapovalov V.V. (Jr.), Shapovalov V.V. (2020). Control regime of drugs for pharmacotherapy of coronavirus disease (COVID-19) in patients with systemic diseases. An information letter about innovations Ukrmedpatentinform of the Ministry of Health of Ukraine. Kyiv: Ukrmedpatentinform of the Ministry of Health of Ukraine, no. 225–2020, 6 p.
7. Hayduchok I.G., Shapovalova V.O., Shapovalov V.V. (Jr.), Shapovalov V.V. (2021) Control regime of drugs for pharmacotherapy vasculitis of Shenlein-Genoch. An information letter about innovations Ukrmedpatentinform of the Ministry of Health of Ukraine. Kyiv: Ukrmedpatentinform of the Ministry of Health of Ukraine, no. 64–2021, 7 p.
8. International Guideline 00449 (2017) Vasculitis. Retrieved from: http://moz.gov.ua/ (accessed 07.05.2018)
9. International Guideline 00653 (2016) Purple Shenlein-Genoch. Retrieved from: http://moz.gov.ua/ (accessed 07.05.2018)
10. Krivenko V. I., Krivenko V. I., Phedorova O. P., Pakhomova S. P. (2018) Systemic vasculitis in the practice of a general practitioner – family medicine. Zaporozhye, 93 p. Retrieved from: http://dspace.zsmu.edu.ua/bitstream (accessed 11.02.2021)
11. Kuzmina A. P. (2015) Systemic vasculitis: a diagnostic search in real clinical practice. Health of Ukraine, vol. 3, no. 40, pp. 42-44.
12. Mamarde A. (2016) ABC/VEN Analysis of drug store in Tertiary care hospital for year 2013-2014. American Journal of Pharmaceutical Research, vol. 6, no. 8, pp. 6439-6444.
13. Management Science for Health. Managing Medicines Selection (2012) Arlington: USA, pp. 161-165.
14. Marushko T. V. (2020) Systemic vasculitis: principles of diagnosis and treatment. Pediatrics, vol. 1, no. 52. Retrieved from: https://health-ua.com/article/46571-sistemn-vaskulti-printcipi-dagnostiki-talkuvannya (accessed 17.01.2021)
15. National list of basic medicines (2009) Resolution of the Cabinet of Ministers of Ukraine no. 333. Retrieved from: http://zakon.rada.gov.ua (accessed 29.03.2011)
16. Order of the Ministry of Health of Ukraine (2020) On approval of the twelfth issue of the State formulary of medicines and ensuring its availability. Dated 06.05.2020 no.1075. Retrieved from: https://zakon.rada.gov.ua (accessed 18.05.2020)
17. Shapovalov (Jr.) V. V., Gudzenko A. A., Andrieieva V. V., Shapovalova V. A., Shapovalov V. V. (2019) Experience of the USA concerning and organization of healthcare system for the pharmaceutical provision for privileged categories of citizens. Annals of Mechnikov Institute, no. 1, pp. 81–87. Retrieved from: http://www.imiamn.org.ua/journal/1_2019/PDF/13.pdf. doi: 10.5281/zenodo.2639521(accessed 24.02.2020)
18. Shapovalov (Jr.) V. V., Gudzenko A. A., Shapovalova V. А., Shapovalov V. V. (2020) Forensic and pharmaceutical analysis of addictive morbidity because of the use of psychoactive substances in Ukraine. Klin. inform. Telemed, vol. 15, no. 16, pp. 125-128. Retrieved from: http://kit–journal.com.ua. doi.org/10.31071/kit2020.16.02 (accessed 22.01.2021)
19. Shapovalov (Jr.) V. V., Shapovalova V. O., Andrieieva V. V., Shapovalov V. V. (2019) Experience of Great Britain in organization of healthcare system for pharmaceutical provision with medicines for privileged categories of citizens. Health of society, vol. 78, no. 1, pp. 36–40. doi: 10.22141/2306-2436.8. 1.2019.172617
20. Shapovalov (Jr.) V., Gudzenko A., Komar L., Butko A., Shapovalova V., Shapovalov V. (2017) Concerning the importance of forensic and pharmaceutical researches to improve patients accessibility to medicines. Pharmacia, vol. 65, no. 2, pp. 23–29.
21. Shapovalov (Jr.) V., Gudzenko A., Shapovalov V., Shapovalova V. (2018) Organizational and legal aspects of the use of pharmacoeconomic analysis of multivitamin complexes for pharmaceutical provision of military personnel. The Pharma Innovation Journal, vol. 7, no. 10, pp. 166–169.
22. Shapovalov (Jr.) V., Gudzenko A., Shapovalova V., Osyntseva A., Shapovalov, V. (2017) Forensic and pharmaceutical study of the presence of a causal link between the degree of alcohol abuse and qualification level of the respondents. Pharmacia, vol. 66, no. 3, pp. 31–39.
23. Shapovalov (Jr.) V., Zbrozhek S., Gudzenko A., Shapovalova V., Shapovalov V. (2018) Organizational and legal analysis of the pharmaceutical provision for the most common diseases of society. International Journal of Pharmaceutical Sciences Review and Research, vol. 51, no. 18, pp. 118-124.
24. Shapovalova V. O., Zbrozhek S. I., Shapovalov (Jr.) V. V., Shapovalov V. V. (2021) Forensic pharmacy: some risk factors in the formation of addictive health disorders. Acta Scientific Pharmaceutical Science, vol. 4, no. 1, pp. 7 – 12. doi: 10.3180 / ASPS.2020.05.0651
25. Shapovalova V. O., Zbrozhek S. I., Shapоvalov V. V. (Jr.), Shapovalov V. V. (2020) Coronavirus disease pandemia 2019: growth of epidemic dangers. Acta scientific pharmaceutical science, vol. 4, no. 7, pp. 61 – 68.
26. Snow John (2005) Logistics Indicators Assessment Tool. Arlington: United States Agency for International Development, 121 p.
27. Vasculitis. Five drugs to control this mysterious blood vessel illness (2017) Retrieved from: https://health.clevelandclinic.org/4-medicines-help-you-manage-the-mysteries-of-vasculitis/ (accessed 19.02.2021)
2. (accessed 20.02.2021)
3. Beketova T.V., Blank L.M., Lila A.M. (2019) COVID-19 in a patient with ANCA-associated systemic vasculitis, receiving anti-B cell therapy (rituximab). Rheumatology Science and Practice. Retrieved from: https://rsp.mediar-press.net/rsp/article/view/2889?locale=ru_RU# (accessed 04.02.2021)
4. Fellner С. (2016) Biologics will pump up the Vasculitis Market. Pharmacy and Therapeutics, vol. 41, no. 4, pp. 258–260. Retrieved from: https://pubmed.ncbi.nlm.nih.gov/27069346/ (accessed 21.12.2020)
5. Hayduchok I.G., Shapovalova V.O., Shapovalov V.V. (Jr.), Shapovalov V.V. (Jr.) (2020) Control regime of antibacterial drugs for pharmacotherapy of coronavirus disease (COVID-19) among patients with dual disorders. An information letter about innovations Ukrmedpatentinform of the Ministry of Health of Ukraine. Kyiv: Ukrmedpatentinform of the Ministry of Health of Ukraine, no. 230–2020, 6 p.
6. Hayduchok I.G., Shapovalova V.O., Shapovalov V.V. (Jr.), Shapovalov V.V. (2020). Control regime of drugs for pharmacotherapy of coronavirus disease (COVID-19) in patients with systemic diseases. An information letter about innovations Ukrmedpatentinform of the Ministry of Health of Ukraine. Kyiv: Ukrmedpatentinform of the Ministry of Health of Ukraine, no. 225–2020, 6 p.
7. Hayduchok I.G., Shapovalova V.O., Shapovalov V.V. (Jr.), Shapovalov V.V. (2021) Control regime of drugs for pharmacotherapy vasculitis of Shenlein-Genoch. An information letter about innovations Ukrmedpatentinform of the Ministry of Health of Ukraine. Kyiv: Ukrmedpatentinform of the Ministry of Health of Ukraine, no. 64–2021, 7 p.
8. International Guideline 00449 (2017) Vasculitis. Retrieved from: http://moz.gov.ua/ (accessed 07.05.2018)
9. International Guideline 00653 (2016) Purple Shenlein-Genoch. Retrieved from: http://moz.gov.ua/ (accessed 07.05.2018)
10. Krivenko V. I., Krivenko V. I., Phedorova O. P., Pakhomova S. P. (2018) Systemic vasculitis in the practice of a general practitioner – family medicine. Zaporozhye, 93 p. Retrieved from: http://dspace.zsmu.edu.ua/bitstream (accessed 11.02.2021)
11. Kuzmina A. P. (2015) Systemic vasculitis: a diagnostic search in real clinical practice. Health of Ukraine, vol. 3, no. 40, pp. 42-44.
12. Mamarde A. (2016) ABC/VEN Analysis of drug store in Tertiary care hospital for year 2013-2014. American Journal of Pharmaceutical Research, vol. 6, no. 8, pp. 6439-6444.
13. Management Science for Health. Managing Medicines Selection (2012) Arlington: USA, pp. 161-165.
14. Marushko T. V. (2020) Systemic vasculitis: principles of diagnosis and treatment. Pediatrics, vol. 1, no. 52. Retrieved from: https://health-ua.com/article/46571-sistemn-vaskulti-printcipi-dagnostiki-talkuvannya (accessed 17.01.2021)
15. National list of basic medicines (2009) Resolution of the Cabinet of Ministers of Ukraine no. 333. Retrieved from: http://zakon.rada.gov.ua (accessed 29.03.2011)
16. Order of the Ministry of Health of Ukraine (2020) On approval of the twelfth issue of the State formulary of medicines and ensuring its availability. Dated 06.05.2020 no.1075. Retrieved from: https://zakon.rada.gov.ua (accessed 18.05.2020)
17. Shapovalov (Jr.) V. V., Gudzenko A. A., Andrieieva V. V., Shapovalova V. A., Shapovalov V. V. (2019) Experience of the USA concerning and organization of healthcare system for the pharmaceutical provision for privileged categories of citizens. Annals of Mechnikov Institute, no. 1, pp. 81–87. Retrieved from: http://www.imiamn.org.ua/journal/1_2019/PDF/13.pdf. doi: 10.5281/zenodo.2639521(accessed 24.02.2020)
18. Shapovalov (Jr.) V. V., Gudzenko A. A., Shapovalova V. А., Shapovalov V. V. (2020) Forensic and pharmaceutical analysis of addictive morbidity because of the use of psychoactive substances in Ukraine. Klin. inform. Telemed, vol. 15, no. 16, pp. 125-128. Retrieved from: http://kit–journal.com.ua. doi.org/10.31071/kit2020.16.02 (accessed 22.01.2021)
19. Shapovalov (Jr.) V. V., Shapovalova V. O., Andrieieva V. V., Shapovalov V. V. (2019) Experience of Great Britain in organization of healthcare system for pharmaceutical provision with medicines for privileged categories of citizens. Health of society, vol. 78, no. 1, pp. 36–40. doi: 10.22141/2306-2436.8. 1.2019.172617
20. Shapovalov (Jr.) V., Gudzenko A., Komar L., Butko A., Shapovalova V., Shapovalov V. (2017) Concerning the importance of forensic and pharmaceutical researches to improve patients accessibility to medicines. Pharmacia, vol. 65, no. 2, pp. 23–29.
21. Shapovalov (Jr.) V., Gudzenko A., Shapovalov V., Shapovalova V. (2018) Organizational and legal aspects of the use of pharmacoeconomic analysis of multivitamin complexes for pharmaceutical provision of military personnel. The Pharma Innovation Journal, vol. 7, no. 10, pp. 166–169.
22. Shapovalov (Jr.) V., Gudzenko A., Shapovalova V., Osyntseva A., Shapovalov, V. (2017) Forensic and pharmaceutical study of the presence of a causal link between the degree of alcohol abuse and qualification level of the respondents. Pharmacia, vol. 66, no. 3, pp. 31–39.
23. Shapovalov (Jr.) V., Zbrozhek S., Gudzenko A., Shapovalova V., Shapovalov V. (2018) Organizational and legal analysis of the pharmaceutical provision for the most common diseases of society. International Journal of Pharmaceutical Sciences Review and Research, vol. 51, no. 18, pp. 118-124.
24. Shapovalova V. O., Zbrozhek S. I., Shapovalov (Jr.) V. V., Shapovalov V. V. (2021) Forensic pharmacy: some risk factors in the formation of addictive health disorders. Acta Scientific Pharmaceutical Science, vol. 4, no. 1, pp. 7 – 12. doi: 10.3180 / ASPS.2020.05.0651
25. Shapovalova V. O., Zbrozhek S. I., Shapоvalov V. V. (Jr.), Shapovalov V. V. (2020) Coronavirus disease pandemia 2019: growth of epidemic dangers. Acta scientific pharmaceutical science, vol. 4, no. 7, pp. 61 – 68.
26. Snow John (2005) Logistics Indicators Assessment Tool. Arlington: United States Agency for International Development, 121 p.
27. Vasculitis. Five drugs to control this mysterious blood vessel illness (2017) Retrieved from: https://health.clevelandclinic.org/4-medicines-help-you-manage-the-mysteries-of-vasculitis/ (accessed 19.02.2021)
Abstract views: 107 PDF Downloads: 131
Published
2021-08-20
How to Cite
Hayduchok, I. (2021). THE USE OF HEPATOPROTECTORS IN THE PHARMACOTHERAPY OF COMORBID VASCULITIS WITH CRYOGLOBULINEMIC SYNDROME. Scientific Journal of Polonia University, 44(1), 252-262. https://doi.org/10.23856/4430
Section
HEALTH, ENVIRONMENT, DEVELOPMENT
