MATERNAL RISK FACTORS OF PERINATAL WOMEN COMPLICATIONS WITH THE URINARY SYSTEM DISEASES
Keywords:
kidney diseases, pregnancy, retrospective analysis
Abstract
The aim of the study was to determine the maternal factors of perinatal complications in women with diseases of the urinary system. A group of women with pathology of the urinary system were studied during the course and completion of pregnancy. The complications in childbirth condition of newborns in comparison with similar indicators in healthy women were also assessed. It was found that most women with urinary tract pathology that were pregnant again, had complications of somatic (most often a combination of urinary tract pathology and chronic infectious diseases) and reproductive history (most often – miscarriages). Women with complications during pregnancy, pyelonephritis, anemia, and the threat of abortion were significantly more often registered in the main group (p<0.05). Women in the main group were significantly more likely to have premature births: 15.4% of women with acute pyelonephritis and 46.2% of women with chronic pyelonephritis, while all women in the control group gave birth on time (P<0.05). Significantly more women in the main group had complications in childbirth: most often – weakness of labor – I group 8 (6.2%), II – 9 (6.9%). Termination of pregnancy in the vast majority of women in the main group was physiological, cesarean delivery was completed in 3 (2.3%) women in group I and 10 (7.7%) women in group II. All women in the control group had timely, physiological births. The condition of newborns of mothers with pathology of the urinary system was often disturbed. A significant proportion of children from the main group (I – 5.4%, II – 10.0%) required immediate resuscitation measures at birth and their transfer to specialized departments for further treatment.
References
1. Bahri A. El., Janane A., Chafiki J. et al. (2015). Acute pyelonephritis in pregnant women: place of medical treatment and indications for drainage of the upper urinary tract (Are there predictive clinical, biological and radiological factors to make the drainage acceptable?). Pan. Afr. Med. J. 22: 324. DOI: 10.11604/pamj.2015.22.324.7262.
2. Bounds K. R., Newell-Rogers M. K., Mitchell B. M. (2015). Four pathways involving innate immunity in the pathogenesis of preeclampsia. Front. Cardiovasc. Med. 2: 20. DOI: 10.3389/ fcvm.2015.00020.
3. Glaser A. P., Schaeffer A. J. (2015). Urinary Tract Infection and Bacteriuria in Pregnancy. Urol. Clin. North. Am. 42, 4: 547–60. DOI: 10.1016/j.ucl.2015.05.004. Godaly G., Ambite I., Svanborg C. (2015). Innate immunity and genetic determinants of urinary tract infection susceptibility. Curr. Opin. Infect. Dis. 28, 1: 88–96. – DOI: 10.1097/QCO.0000000000000127.
4. Govoruha I. T., Stepanenko T.A. (2013). Faktory riska razvitiya pielonefrita u beremennyh s bessimptomnoj bakteriuriej. [Risk factors for the development of pyelonephritis in pregnant women with asymptomatic bacteriuria] Medyko-sotsialni problemy simi. 18; 4: 16–18. [in Ukrainian].
5. Haistruk N.A., Suprunova T.V., Nadezhdin M.V., Ponina S.I. (2017). Osoblyvosti perebihu vahitnosti ta stan ploda u vahitnykh z hestatsiinym ta khronichnym piielonefrytom. [Peculiarities of pregnancy and fetal condition in pregnant women with gestational and chronic pyelonephritis]. Journal of Education, Health and Sport. 7, 1: 423–436. [in Ukrainian].
6. Holubenko M. Yu. (2012). Vyvchennia etiolohichnykh chynnykiv PD u zhinok z piielonefrytom. [Study of etiological factors of PD in women with pyelonephritis]. Aktualni problemy transportnoi medytsyny: navkolyshnie seredovyshche; profesiine zdorovia; patolohiia. 2: 87–91. [in Ukrainian].
7. Hryhorenko A.P., Shymanska–Horbatiuk O.H., Shatkovska N.S. [ta in.]. (2014). Vahitnist ta infektsii sechovyvidnoi systemy. [Pregnancy and urinary tract infections]. Medicinskie aspekty zdorov’ya zhenshchiny 6: 24–32. [in Ukrainian].
8. Kazemier B. M., Koningstein F. N., Schneeberger C. et al. (2015). Maternal and neonatal consequences of treated and untreated asymptomatic bacteriuria in pregnancy: a prospective cohort study with an embedded randomised controlled trial. Lancet Infect. Dis. 15, 11: 1324–1333. DOI: 10.1016/S1473-3099(15)00070-5.
9. Limanskaya A.YU., Shevchuk E.V., Ogorodnik A.A., Davydova YU.V. (2016). Prekoncepcionnaya profilaktika infekcij mochevyh putej u zhenshchin gruppy vysokogo riska: rezerv snizheniya perinatal’nyh i akusherskih oslozhnenij. [ Preconception prevention of urinary tract infections in high-risk women: a reserve for reducing perinatal and obstetric complications]. Perynatolohiia ta pediatriia. 2: 28–31. http://nbuv.gov.ua/UJRN/perynatology_2016_2_9. [in Ukrainian].
10. Mandal D., Saha M. M., D. K. (2017). Pal Urological disorders and pregnancy: an overall experience. Urol Ann. 9, 1: 32–36. DOI: 10.4103/0974-7796.198901.
11. Melenchuk L. M., Chorna L.B. (2019). Rozrobka systemy efektyvnoho prohnozuvannia, rannoi diahnostyky i profilaktyky perynatalnoi patolohii v zhinok iz patolohiieiu sechovydilnoi systemy zalezhno vid henotypu polimorfnykh variantiv hena VEGF. [Development of a system for effective prediction, early diagnosis and prevention of perinatal pathology in women with pathology of the urinary system depending on the genotype of polymorphic variants of the VEGF gene]. Aktualni pytannia pediatrii, akusherstva ta hinekolohii. 1: 119-125. DOI: https://doi.org/10.11603/24116-4944.2019.1.10198. [in Ukrainian].
12. Olshevska O.V., Olshevskyi V.S. (2016). Osoblyvosti fetalnoi adaptatsii pry khronichnomu piielonefryti ta preeklampsii na tli khronichnoho piielonefrytu. [Features of fetal adaptation in chronic pyelonephritis and preeclampsia on the background of chronic pyelonephritis]. Ukrainskyi zhurnal khirurhii. 1-2 (30-31): 68-71. [in Ukrainian].
13. Romanenko T. H. (2016). Korektsiia PD u vahitnykh z piielonefrytom. [Correction of PD in pregnant women with pyelonephritis.] Zdorov’e zhenshchiny. 1: 86–90. [in Ukrainian].
14. Safonova I. M. (2015). Postnatalni klinichni rezultaty riznykh ekhohrafichnykh variantiv anomalii sechovydilnoi systemy ploda: ohliad literatury i analiz serii vypadkiv.[Postnatal clinical results of various ultrasound variants of fetal urinary system abnormalities: literature review and case series analysis]. Ukrainskyi radiolohichnyi zhurnal. 23, 1: 80-83. http://nbuv.gov.ua/UJRN/URLZh_2015_23_1_16. [in Ukrainian].
15. Samigullina A. E., Otogonova ZH.K. (2016). Rol’ pielonefritov v razvitii akusherskih oslozhnenij: obzor literatury. [The role of pyelonephritis in the development of obstetric complications: a literature review] Izvestiya vuzov. 7. 1: 36–38. [in Kyrgystan].
16. Sharhorodska Ye.B., Shkolnyk O.S. (2018). Retrospektyvnyi analiz perebihu vahitnosti v zhinok, shcho narodyly ditei iz vrodzhenoiu patolohiieiu systemy krovoobihu. [Retrospective analysis of pregnancy in women who gave birth to children with congenital pathology of the circulatory system]. Aktualni pytannia pediatrii, akusherstva ta hinekolohii. 2: 100-104. DOI: https://doi.org/10.11603/24116-4944.2018.2.9206. [in Ukrainian].
17. Shestakova T. S. (2012). Osobennosti gestacionnyh oslozhnenij u beremennyh s hronicheskim pielonefritom. [Features of gestational complications in pregnant women with chronic pyelonephritis]. Aktualni pytannia farmatsevtychnoi i medychnoi nauky ta praktyky. 2, 2: 163. [in Ukrainian].
18. Szweda H., Jóźwik M. (2016). Urinary tract infections during pregnancy – an updated overview. Dev. Period. Med. 20, 4: 263–272.
19. Talalaienko Yu. O., Yulish Ye. I., Talalaienko O. K. (2014). Piielonefryt, platsenta i novonarodzhenyi : ohliad literatury. [Pyelonephritis, placenta and newborn: a review of the literature]. Medyko-sotsialni problemy simi.19, 1: 98–103. [in Ukrainian].
20. Tillett J. (2015). Increasing morbidity in the pregnant population in the United States 29, 3: 191–193. DOI: 10.1097/JPN.0000000000000116.
21. Veropotvelian M.P., Kodunov L. O., Pohuliai Yu. S. (2016). Sezonni osoblyvosti formuvannia khromosomnoi patolohii u Tsentralnomu ta Pivdenno-Skhidnomu rehionakh Ukrainy: retrospektyvnyi analiz za 20 rokiv. [Seasonal features of chromosomal pathology formation in the Central and South-Eastern regions of Ukraine: a retrospective analysis for 20 years]. Zdorove zhenshchynы4: 91-97. http://nbuv.gov.ua/UJRN/Zdzh_2016_4_17.
22. Veropotvelian P. M., Vyshnevskyi I. Ye., Veropotvelian M. P. ta in. (2011). Suchasnyi pohliad na perebih vahitnosti ta polohiv, uskladnenyi piielonefrytom : ohliad literatury ta vlasni doslidzhennia. [Modern view of pregnancy and childbirth complicated by pyelonephritis: a review of the literature and our own research]. Pediatriia, akusherstvo ta hinekolohiia. 73, 4: 202–210. [in Ukrainian].
23. Wing D. A., Fassett M. J., Getahun D. (2014). Acute pyelonephritis in pregnancy: an 18-year retrospective analysis. Am. J. Obstet. Gynecol. 210, 3: 219.e1–219.e6. DOI: 10.1016/j.ajog.2013.10.006.
2. Bounds K. R., Newell-Rogers M. K., Mitchell B. M. (2015). Four pathways involving innate immunity in the pathogenesis of preeclampsia. Front. Cardiovasc. Med. 2: 20. DOI: 10.3389/ fcvm.2015.00020.
3. Glaser A. P., Schaeffer A. J. (2015). Urinary Tract Infection and Bacteriuria in Pregnancy. Urol. Clin. North. Am. 42, 4: 547–60. DOI: 10.1016/j.ucl.2015.05.004. Godaly G., Ambite I., Svanborg C. (2015). Innate immunity and genetic determinants of urinary tract infection susceptibility. Curr. Opin. Infect. Dis. 28, 1: 88–96. – DOI: 10.1097/QCO.0000000000000127.
4. Govoruha I. T., Stepanenko T.A. (2013). Faktory riska razvitiya pielonefrita u beremennyh s bessimptomnoj bakteriuriej. [Risk factors for the development of pyelonephritis in pregnant women with asymptomatic bacteriuria] Medyko-sotsialni problemy simi. 18; 4: 16–18. [in Ukrainian].
5. Haistruk N.A., Suprunova T.V., Nadezhdin M.V., Ponina S.I. (2017). Osoblyvosti perebihu vahitnosti ta stan ploda u vahitnykh z hestatsiinym ta khronichnym piielonefrytom. [Peculiarities of pregnancy and fetal condition in pregnant women with gestational and chronic pyelonephritis]. Journal of Education, Health and Sport. 7, 1: 423–436. [in Ukrainian].
6. Holubenko M. Yu. (2012). Vyvchennia etiolohichnykh chynnykiv PD u zhinok z piielonefrytom. [Study of etiological factors of PD in women with pyelonephritis]. Aktualni problemy transportnoi medytsyny: navkolyshnie seredovyshche; profesiine zdorovia; patolohiia. 2: 87–91. [in Ukrainian].
7. Hryhorenko A.P., Shymanska–Horbatiuk O.H., Shatkovska N.S. [ta in.]. (2014). Vahitnist ta infektsii sechovyvidnoi systemy. [Pregnancy and urinary tract infections]. Medicinskie aspekty zdorov’ya zhenshchiny 6: 24–32. [in Ukrainian].
8. Kazemier B. M., Koningstein F. N., Schneeberger C. et al. (2015). Maternal and neonatal consequences of treated and untreated asymptomatic bacteriuria in pregnancy: a prospective cohort study with an embedded randomised controlled trial. Lancet Infect. Dis. 15, 11: 1324–1333. DOI: 10.1016/S1473-3099(15)00070-5.
9. Limanskaya A.YU., Shevchuk E.V., Ogorodnik A.A., Davydova YU.V. (2016). Prekoncepcionnaya profilaktika infekcij mochevyh putej u zhenshchin gruppy vysokogo riska: rezerv snizheniya perinatal’nyh i akusherskih oslozhnenij. [ Preconception prevention of urinary tract infections in high-risk women: a reserve for reducing perinatal and obstetric complications]. Perynatolohiia ta pediatriia. 2: 28–31. http://nbuv.gov.ua/UJRN/perynatology_2016_2_9. [in Ukrainian].
10. Mandal D., Saha M. M., D. K. (2017). Pal Urological disorders and pregnancy: an overall experience. Urol Ann. 9, 1: 32–36. DOI: 10.4103/0974-7796.198901.
11. Melenchuk L. M., Chorna L.B. (2019). Rozrobka systemy efektyvnoho prohnozuvannia, rannoi diahnostyky i profilaktyky perynatalnoi patolohii v zhinok iz patolohiieiu sechovydilnoi systemy zalezhno vid henotypu polimorfnykh variantiv hena VEGF. [Development of a system for effective prediction, early diagnosis and prevention of perinatal pathology in women with pathology of the urinary system depending on the genotype of polymorphic variants of the VEGF gene]. Aktualni pytannia pediatrii, akusherstva ta hinekolohii. 1: 119-125. DOI: https://doi.org/10.11603/24116-4944.2019.1.10198. [in Ukrainian].
12. Olshevska O.V., Olshevskyi V.S. (2016). Osoblyvosti fetalnoi adaptatsii pry khronichnomu piielonefryti ta preeklampsii na tli khronichnoho piielonefrytu. [Features of fetal adaptation in chronic pyelonephritis and preeclampsia on the background of chronic pyelonephritis]. Ukrainskyi zhurnal khirurhii. 1-2 (30-31): 68-71. [in Ukrainian].
13. Romanenko T. H. (2016). Korektsiia PD u vahitnykh z piielonefrytom. [Correction of PD in pregnant women with pyelonephritis.] Zdorov’e zhenshchiny. 1: 86–90. [in Ukrainian].
14. Safonova I. M. (2015). Postnatalni klinichni rezultaty riznykh ekhohrafichnykh variantiv anomalii sechovydilnoi systemy ploda: ohliad literatury i analiz serii vypadkiv.[Postnatal clinical results of various ultrasound variants of fetal urinary system abnormalities: literature review and case series analysis]. Ukrainskyi radiolohichnyi zhurnal. 23, 1: 80-83. http://nbuv.gov.ua/UJRN/URLZh_2015_23_1_16. [in Ukrainian].
15. Samigullina A. E., Otogonova ZH.K. (2016). Rol’ pielonefritov v razvitii akusherskih oslozhnenij: obzor literatury. [The role of pyelonephritis in the development of obstetric complications: a literature review] Izvestiya vuzov. 7. 1: 36–38. [in Kyrgystan].
16. Sharhorodska Ye.B., Shkolnyk O.S. (2018). Retrospektyvnyi analiz perebihu vahitnosti v zhinok, shcho narodyly ditei iz vrodzhenoiu patolohiieiu systemy krovoobihu. [Retrospective analysis of pregnancy in women who gave birth to children with congenital pathology of the circulatory system]. Aktualni pytannia pediatrii, akusherstva ta hinekolohii. 2: 100-104. DOI: https://doi.org/10.11603/24116-4944.2018.2.9206. [in Ukrainian].
17. Shestakova T. S. (2012). Osobennosti gestacionnyh oslozhnenij u beremennyh s hronicheskim pielonefritom. [Features of gestational complications in pregnant women with chronic pyelonephritis]. Aktualni pytannia farmatsevtychnoi i medychnoi nauky ta praktyky. 2, 2: 163. [in Ukrainian].
18. Szweda H., Jóźwik M. (2016). Urinary tract infections during pregnancy – an updated overview. Dev. Period. Med. 20, 4: 263–272.
19. Talalaienko Yu. O., Yulish Ye. I., Talalaienko O. K. (2014). Piielonefryt, platsenta i novonarodzhenyi : ohliad literatury. [Pyelonephritis, placenta and newborn: a review of the literature]. Medyko-sotsialni problemy simi.19, 1: 98–103. [in Ukrainian].
20. Tillett J. (2015). Increasing morbidity in the pregnant population in the United States 29, 3: 191–193. DOI: 10.1097/JPN.0000000000000116.
21. Veropotvelian M.P., Kodunov L. O., Pohuliai Yu. S. (2016). Sezonni osoblyvosti formuvannia khromosomnoi patolohii u Tsentralnomu ta Pivdenno-Skhidnomu rehionakh Ukrainy: retrospektyvnyi analiz za 20 rokiv. [Seasonal features of chromosomal pathology formation in the Central and South-Eastern regions of Ukraine: a retrospective analysis for 20 years]. Zdorove zhenshchynы4: 91-97. http://nbuv.gov.ua/UJRN/Zdzh_2016_4_17.
22. Veropotvelian P. M., Vyshnevskyi I. Ye., Veropotvelian M. P. ta in. (2011). Suchasnyi pohliad na perebih vahitnosti ta polohiv, uskladnenyi piielonefrytom : ohliad literatury ta vlasni doslidzhennia. [Modern view of pregnancy and childbirth complicated by pyelonephritis: a review of the literature and our own research]. Pediatriia, akusherstvo ta hinekolohiia. 73, 4: 202–210. [in Ukrainian].
23. Wing D. A., Fassett M. J., Getahun D. (2014). Acute pyelonephritis in pregnancy: an 18-year retrospective analysis. Am. J. Obstet. Gynecol. 210, 3: 219.e1–219.e6. DOI: 10.1016/j.ajog.2013.10.006.
Abstract views: 163 PDF Downloads: 160
Published
2021-06-18
How to Cite
Melenchuk, L., & Sharhorodska, Y. (2021). MATERNAL RISK FACTORS OF PERINATAL WOMEN COMPLICATIONS WITH THE URINARY SYSTEM DISEASES. Scientific Journal of Polonia University, 43(6), 269-278. https://doi.org/10.23856/4335
Section
HEALTH, ENVIRONMENT, DEVELOPMENT
